Cytochrome P450 Monooxygenase in Plant Defense Mechanisms against Insect Pests

Plant–insect interactions have been shaped by millions of years of coevolution, leading to a diverse array of defense mechanisms in plants to fend off herbivorous insects. These mechanisms, one such mechanism involves the cytochrome P450 (CYP) monooxygenase superfamily of enzymes, which are essential in the metabolism of endogenous compounds and exogenous toxins. This chapter explores the importance of plant CYPs as a versatile and critical component of the plant defense arsenal against insect pests. It examines the molecular mechanisms underlying CYP-mediated detoxification and discusses the impact of various factors on their effectiveness. Furthermore, this chapter delves into the potential applications of this knowledge in sustainable pest management strategies to reduce the reliance on chemical insecticides and promote environmentally friendly agricultural practices.