Structural Bioinformatics

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Authors: Firdous Fatima, Sunita Dahiya, Arun K. Iyer, Rajiv Dahiya
Cited by: 0

Abstract

Structural bioinformatics is a field of science that uses computers to analyze and predict the 3D shapes of giant molecules like proteins and DNA. Scientists can use real-world data or computer models to study these shapes. This helps them understand how these molecules fold, how they interact with each other, and how their shape relates to their function. The main goal of structural bioinformatics is to develop new methods for analyzing this data to solve biological puzzles and make new discoveries. For many years, scientists have been trying to predict the 3D shape of proteins just by knowing their amino acid sequence. This is a difficult problem but solving it could have many benefits, such as helping us understand genes and how proteins work. With faster computers and more data on proteins, scientists have developed new methods to predict protein shapes. Furthermore, it is essential to design novel proteins with tailored functionalities, such as fluorescent proteins for biomedical research or therapeutic proteins intended for clinical applications.

Fields of Study & Subjects

Protein Structure and Dynamics Genetics Bioinformatics and Biomedical Research Machine Learning in Bioinformatics

Publication details

Pages
13–26
Publication date
9 January 2026
Language
EN
Document type
Book chapter