Catharanthus Roseus

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Authors: Sonali Purohit, Arun Kumar Khajuria, Akshay Gautam, Rakesh Kumar Bachheti, Archana Bachheti, Anuj Kandwal
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Abstract

Catharanthus roseus is a well-known medicinal plant belonging to the Apocynaceae family. Alkaloids, which are found throughout the plant, are abundant in it. The highest alkaloid content of Catharanthus roseus is found in the root bark, as high as 1.79%. Vincristine and vinblastine, two dimeric alkaloids primarily found in the aerial parts, have been widely used to treat human neoplasms. Ajmalicine, one of the monomeric alkaloids present in the roots, has been shown to have a wide range of uses in the management of circulatory disorders, particularly in alleviating blockages in normal cerebral blood flow. In addition to neuroblastoma, choriocarcinoma, lymphosarcoma, and carcinoma of the lungs, breasts, and other organs in acute and chronic leukaemia, vinblastine is explicitly used to treat Hodgkin's disease. Catharanthus roseus is a significant medication. In many nations (India, Mexico, Brazil, West Indies, Kenya, China, Peru, Taiwan, England, Europe, France, Guinea, Jamaica, South Africa, Vietnam, America, etc.), several parts of it have historically been used to treat a variety of illnesses, including diabetes, menstrual regulators, hypertension, etc.

Fields of Study & Subjects

Alkaloids: synthesis and pharmacology Phytochemistry and Bioactive Compounds Medicinal Plant Research

Publication details

Journal / source
CRC Press eBooks
Pages
129–138
Publication date
10 February 2026
Language
EN
Document type
Book chapter