Confinement-driven acceleration of first-passage rates
Abstract
Abstract We demonstrate that confinement geometry can optimally accelerate first-passage rates beyond free diffusion in passive stochastic processes. Introducing generalized confinement model based on the Fick-Jacobs approach and simulations, we find nonmonotonic mean first-passage rates driven by confinement geometry and curvature. Through the transmission probability, our findings highlight how confinement optimizes transport dynamics in trap-and-escape processes, with implications for molecular translocation and reaction kinetics in soft matter and biological systems.
Fields of Study & Subjects
stochastic dynamics and bifurcation
Diffusion and Search Dynamics
Stochastic processes and statistical mechanics
Publication details
- Journal / source
- Europhysics Letters (EPL)
- Volume
- 153
- Issue
- 4
- Pages
- 47002–47002
- Publication date
- 1 February 2026
- Language
- EN