Glucocorticoid trajectories in preterm infants—born too soon, wired differently

The Journal of Clinical Endocrinology & Metabolism 2026 Open access

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Authors: Tanja Kuiri-Hänninen, Christa E. Flück, Sanna Silvennoinen, Michael Groessl, Ulla Sankilampi
DOI: 10.1210/clinem/dgag048
Cited by: 2
References: 55

Abstract

CONTEXT: Levels of glucocorticoid (GC) precursors are elevated in preterm infants, whereas clinical signs of GC deficiency are frequently observed in neonatal intensive care units. OBJECTIVE: To describe the maturation of the GC metabolic pathway in preterm infants during the first year of life. DESIGN AND SETTING: Spot urinary samples (n = 154) were collected in the neonatal intensive care unit and at follow-up visits. PARTICIPANTS: Sixteen preterm infants (8 boys) born

Fields of Study & Subjects

Infant Nutrition and Health Neonatal Respiratory Health Research Birth Development and Health

Publication details

Journal / source
The Journal of Clinical Endocrinology & Metabolism
Publisher
The Endocrine Society
Volume
111
Issue
7
Pages
1908–1919
Publication date
12 February 2026
Language
EN