Acromegaly complications: an update
Abstract
CONTEXT: Appropriate diagnosis and treatment of comorbidities is key to managing acromegaly given their adverse clinical impact on quality of life and survival; thus, it is important to increase overall awareness of complications and their individualized management. EVIDENCE: This review examines the current literature on pathophysiology, diagnosis, and clinical presentation of acromegaly complications, as well as impact of acromegaly therapy and current goals for treatment outcomes of these morbidities. CONCLUSION: We focus on the most relevant acromegaly comorbidities including cardiorespiratory, metabolic, bone, and oncologic complications. Selected complications that may determine pharmacologic choices are also evaluated.
Fields of Study & Subjects
Pituitary Gland Disorders and Treatments
Adrenal and Paraganglionic Tumors
Coagulation
Bradykinin
Polyphosphates
and Angioedema
Publication details
- Journal / source
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Volume
- 111
- Issue
- Supplement_1
- Pages
- S51–S63
- Publication date
- 18 March 2026
- Language
- EN