The important role of comorbidities in the management of obesity

Read full text
Authors: Sarah R. Barenbaum, Beverly G. Tchang, Louis J. Aronne
Cited by: 3
References: 76

Abstract

Obesity is a chronic, multifactorial disease associated with more than 200 complications including type 2 diabetes, cardiovascular disease, obstructive sleep apnea, dyslipidemia, hypertension, premature mortality, and numerous other adverse effects spanning multiple organ systems. In addition to these health complications, obesity also contributes to weight stigma and bias, which negatively affect access to care, treatment outcomes, and quality of life. Together, these complications and social consequences drive high morbidity, premature mortality, and increasing healthcare costs. Early diagnosis of obesity and systematic screening for related conditions are essential to improving health outcomes. Clinicians must treat obesity in addition to managing its complications, offering individualized strategies that may include lifestyle modification, pharmacotherapy, and bariatric surgery. Because obesity is a chronic and relapsing disease, effective management requires long-term follow-up and coordinated care through a multidisciplinary team. The effective treatment of obesity and its comorbidities can improve individual health outcomes, reduce healthcare costs, and reduce the global burden of chronic disease.

Fields of Study & Subjects

Pharmacology and Obesity Treatment Bariatric Surgery and Outcomes Obesity and Health Practices

Publication details

Journal / source
Journal of the Endocrine Society
Publisher
The Endocrine Society
Volume
10
Issue
3
Pages
bvag012–bvag012
Publication date
17 January 2026
Language
EN