Preoperative eGFR, age, and sex predict early postoperative renal changes in acromegaly

Journal of the Endocrine Society 2026 Open access

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Authors: Keiko Tomiyama, Izumi Fukuda, Mikiko Okazaki‐Hada, Shunsuke Kobayashi, Mototsugu Nagao, Shigeyuki Tahara, Masato Iwabu
DOI: 10.1210/jendso/bvag126
Cited by: 1
References: 22

Abstract

Abstract Objective Acromegaly induces renal alterations. However, early postoperative renal changes following rapid hormonal correction remain unclear. We assessed early postoperative changes in estimated glomerular filtration rate (eGFR) and their associated factors, focusing on preoperative eGFR, age, and sex. Methods We retrospectively analyzed 44 patients with acromegaly who underwent trans-sphenoidal surgery between 2012 and 2024. We analyzed renal function using preoperative eGFR and changes in eGFR at postoperative day 14 (POD14) relative to preoperative values (ΔeGFR). Patients were stratified by preoperative eGFR (≥ 90 vs

Fields of Study & Subjects

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Publication details

Journal / source
Journal of the Endocrine Society
Publisher
The Endocrine Society
Volume
10
Issue
7
Pages
bvag126–bvag126
Publication date
29 May 2026
Language
EN