Drug-induced Cardiotoxicity in the Chinese Population: Current Analysis and Considerations

Pharmacogenetic cardiotoxicity is one of the most common and serious clinical adverse drug reactions and an important risk factor for cardiovascular disease. At present, highly specific and sensitive early predictive indicators and effective preventive and curative drugs are still lacking. It is of great significance to understand the current situation of the occurrence of drug-induced cardiotoxicity in China, to explore the clinical evaluation indices for early detection, and to summarize the measures to reduce toxicity and increase efficacy in order to improve cardiac injury and enhance drug safety. The purpose of this paper is to systematically summarize the clinical status of drug-induced cardiotoxicity in China, list in detail the drugs with definite or potential cardiotoxicity, and explore the mechanisms of their toxicity. At the same time, it focuses on the early monitoring and warning of drug-induced cardiotoxicity, and summarizes the prevention and treatment measures in Chinese and Western medicine, which provide valuable references for its early detection and early intervention.