Automated Imaging Differentiation for Dementia

Neurology Open Access 2026 Open access

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Authors: Robin Chen, Shannon Chiu, Jesse C. DeSimone, Wei Wang, Angelos Barmpoutis, Corey T. McMillan, Hamsanandini Radhakrishnan, David John Irwin, Lyles Clark, Kejal Kantarci, Bradley F. Boeve, David E. Vaillancourt
DOI: 10.1212/wn9.0000000000000093
Cited by: 1
References: 49

Abstract

Differentiation of Alzheimer disease dementia (ADD) and dementia with Lewy bodies (DLB) remains a challenge. Free-water (FW) imaging has been investigated in neurodegenerative diseases and was found to be associated with neurodegeneration and neuroinflammation. This retrospective cohort study tested whether Automated Imaging Differentiation for Dementia (AIDD), combining diffusion free-water imaging (FWI) and support vector machine, predicts ADD vs DLB with high accuracy.

Fields of Study & Subjects

Dementia and Cognitive Impairment Research Brain Tumor Detection and Classification EEG and Brain-Computer Interfaces

Publication details

Journal / source
Neurology Open Access
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
2
Issue
2
Publication date
13 April 2026
Language
EN