Expanding the Clinical Phenotypes of Corticobasal Degeneration

Neurology Open Access 2026 Open access

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Authors: Emma Wetmore, Gokhan Uruk, Jerusha Bhaskaran, J Desmond O Duffy, David S. Knopman, Bradley F. Boeve, Ronald C. Petersen, Aivi T. Nguyen, R. Ross Reichard, Dennis W. Dickson, Jennifer L. Whitwell, Keith A. Josephs
DOI: 10.1212/wn9.0000000000000110
Cited by: 1
References: 37

Abstract

Corticobasal degeneration (CBD) is a rare, progressive neurodegenerative disease associated with a variety of cognitive and motor features. International consensus criteria define 5 clinical phenotypes of CBD. It is unknown whether there are other “atypical” presentations of CBD and whether these atypical presentations have unique neuroanatomic and/or neuropathologic features. The objectives of this study were to determine whether atypical presentations of CBD exist and, if so, examine such presentations and identify neuroanatomic and histopathologic features that could account for such presentations.

Fields of Study & Subjects

Neurological diseases and metabolism Parkinson's Disease Mechanisms and Treatments Amyotrophic Lateral Sclerosis Research

Publication details

Journal / source
Neurology Open Access
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
2
Issue
2
Publication date
1 June 2026
Language
EN