Phase III Trial of EpiWatch for Tonic-Clonic Seizure Detection in Children and Adults

Neurology Open Access 2026 Open access

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Authors: Gregory L. Krauss, Reena Elizebath, Samyak Shah, James W. Wheless, Michael R. Sperling, Dewi Frances Depositario Cabacar, William D. Gaillard, Neel Parikh, Richard Chiacchierini, Nathan E. Crone
DOI: 10.1212/wn9.0000000000000111
Cited by: 1
References: 32

Abstract

Risks of sudden unexpected death in epilepsy are high in individuals with uncontrolled tonic-clonic seizures (TCSs), particularly in those who sleep alone. Wearable seizure detection devices can alert caregivers to provide timely intervention; however, current devices risk stigma and have high false alarm rates (FARs) that discourage consistent use and caregiver responses. EpiWatch is a seizure detection application (app) developed for the Apple Watch, designed to minimize FAR without compromising detection sensitivity or latency. We evaluated the sensitivity and FAR of EpiWatch for detecting TCSs in children and adults undergoing video-EEG monitoring.

Fields of Study & Subjects

Epilepsy research and treatment EEG and Brain-Computer Interfaces Neurological disorders and treatments

Publication details

Journal / source
Neurology Open Access
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
2
Issue
2
Publication date
27 May 2026
Language
EN