A Novel Mechanism for the Treatment of Autoimmune Neurologic Diseases: Robust, Rapid, and Tunable Removal of IgG with the MoDE™ Degrader BHV-1300 (P5-2.004)

Neurology 2026

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Authors: Bharat Awsare, Volkan Granit, Eric Ashbrenner, Randall Killingsworth, Richard Bertz, Bruce Car, David Spiegel, Tova Gardin, Vladimir Coric
DOI: 10.1212/wnl.0000000000216812
Cited by: 1

Abstract

Key objectives included assessments of safety, pharmacokinetics, and pharmacodynamic markers of BHV-1300.

Fields of Study & Subjects

Peripheral Neuropathies and Disorders Monoclonal and Polyclonal Antibodies Research Multiple Sclerosis Research Studies

Publication details

Journal / source
Neurology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
106
Issue
11_Supplement_1
Publication date
9 June 2026
Language
EN