Contribution of Acute Kidney Injury After Liver Transplant in Development of Chronic Kidney Disease: A Single-Center Retrospective Cohort Study

Anesthesia & Analgesia 2026

View at publisher
Authors: Nicholas V. Mendez, Daniel Chan, Trina Thompson, David Chen, Sebastian Zeiner, Rishi P. Kothari, Hillary J. Braun, Michael P. Bokoch, Kerstin Kolodzie, Dieter Adelmann
DOI: 10.1213/ane.0000000000007911
Cited by: 1
References: 33

Abstract

BACKGROUND: Acute kidney injury (AKI) is common after liver transplant and associated with increased morbidity and mortality. Transplantation of nonrenal organs is also associated with eventual chronic kidney disease (CKD). Development of CKD after liver transplant is known to be multifactorial; however, this study evaluates the unique contribution of AKI in this complex disease pathway. METHODS: Patients were classified into 2 groups: presence or absence of severe AKI within 72 hours postoperatively. Kidney function was assessed at year 1: normal/mild (estimated glomerular filtration rate [eGFR] ≥60 mL/min/1.73 m 2 ); moderate (30 ≤eGFR

Fields of Study & Subjects

Liver Disease and Transplantation Renal Transplantation Outcomes and Treatments Organ Transplantation Techniques and Outcomes

Publication details

Journal / source
Anesthesia & Analgesia
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
142
Issue
5
Pages
938–946
Publication date
26 January 2026
Language
EN