The people behind the papers – Esther Ushuhuda and Maria Mikedis
Abstract
MEIOC, which is part of an RNA-binding complex, regulates meiosis-associated genes through STRA8-MEIOSIN during spermatogenesis. In their work, Maria Mikedis and colleagues show that MEIOC initiates the mitosis-to-meiosis transition in mammalian oocytes by repressing the mitotic cyclin CCNA2 and promoting the STRA8-MEIOSIN pathway. To learn about their work, we spoke to the first author, Esther Ushuhuda, and the corresponding author, Maria Mikedis, Assistant Professor, UC Department of Pediatrics, Cincinnati Children's Hospital, USA.
Fields of Study & Subjects
Reproductive Biology and Fertility
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Sperm and Testicular Function
Publication details
- Journal / source
- Development
- Volume
- 153
- Issue
- 1
- Publication date
- 1 January 2026
- Language
- EN