Generating cerebellar organoids from pluripotent stem cells
Abstract
Cerebellar organoids present promising tools for the modelling of human cerebellar development and diseases. As this young field grows, robust standards and transparent reporting practices are needed to ensure the reproducibility and utility of the generated cerebellar organoid models. Here, we summarize current approaches to generate cerebellar organoids and their applications. We suggest common quality control standards and biological readouts that should be considered in this emerging area.
Fields of Study & Subjects
Pluripotent Stem Cells Research
Neurogenesis and neuroplasticity mechanisms
Developmental Biology and Gene Regulation
Publication details
- Journal / source
- Disease Models & Mechanisms
- Volume
- 19
- Issue
- 1
- Publication date
- 1 January 2026
- Language
- EN