Evaluation of Exercise Tolerance in Cancer Patients With Cardiovascular Complications ― A Japanese Single-Center Retrospective Study Using Cardiopulmonary Exercise Testing ―

Circulation Reports 2026 Open access

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Authors: Asaki Saijo, Hidetaka Itoh, Yuko Tanabe, Chinatsu Komiyama, Ayako Harima, Tetsuo Yamaguchi, Yasuhiro Tomita, Yuji Miura, Takahide Kodama
DOI: 10.1253/circrep.cr-25-0331
Cited by: 0
References: 36

Abstract

Background: Despite growing interest in cardio-oncology rehabilitation (CORE), data on cardiopulmonary exercise testing (CPX/CPET) in Japanese cancer patients remain scarce. Methods and Results: slope 30.7, indicating reduced cardiorespiratory function. No significant differences were observed between the CTRCD and non-CTRCD groups. In 4 patients with serial CPX, exercise capacity changes did not always parallel left ventricular ejection fraction. Conclusions: In cancer patients with cardiovascular problems, CPX revealed reduced exercise tolerance beyond cardiac function. These findings highlight the need for individualized rehabilitation inform future CORE protocols.

Fields of Study & Subjects

Cardiovascular and exercise physiology Cardiac Health and Mental Health Cancer survivorship and care

Publication details

Journal / source
Circulation Reports
Volume
8
Issue
5
Pages
710–718
Publication date
4 March 2026
Language
EN