Comparison of Landiolol and Verapamil for Postoperative Atrial Fibrillation ― A Prospective Randomized Study ―

Circulation Reports 2026 Open access

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Authors: Naoto Yabu, Tomoyuki Minami, Shota Yasuda, Yoshiyuki Kobayashi, Aya Saito
DOI: 10.1253/circrep.cr-25-0335
Cited by: 0
References: 4

Abstract

Background: Postoperative atrial fibrillation (POAF) after cardiac surgery requires prompt intervention. We compared landiolol with verapamil for POAF treatment. Methods and Results: This randomized trial enrolled 179 patients; 45 developed POAF. Landiolol achieved higher sinus rhythm conversion at 8 h (73.3% vs 16.7%; P=0.0016), but not at 12 h. No differences were observed in recurrence, adverse events, or intensive care unit stay. Conclusions: Landiolol facilitates earlier rhythm conversion without clear short-term clinical benefit.

Fields of Study & Subjects

Atrial Fibrillation Management and Outcomes Cardiac Arrhythmias and Treatments Cardiac Anesthesia and Surgical Outcomes

Publication details

Journal / source
Circulation Reports
Volume
8
Issue
4
Pages
680–682
Publication date
9 February 2026
Language
EN