Clinical Factors Associated With Positive 99 mTc-Pyrophosphate Scintigraphy Beyond Kumamoto Criteria in a Real-World Cohort
Abstract
Background: Tc-pyrophosphate (PYP) uptake, but real-world performance is uncertain. Methods and Results: We reviewed 102 consecutive patients who underwent PYP scintigraphy; grade ≥2 was positive, and grade 1 equivocal/negative. Of them, 15 were positive; 11 had scores 0-1 yet were positive, while 8 scored 2 and yet were negative. Adding age, sex, PR interval, and atrial fibrillation improved the area under the curve (AUC) from 0.598 to 0.866; excluding sex yielded AUC 0.842. Conclusions: Using the Kumamoto criteria alone showed limited discrimination; combining routine variables may help select patients for PYP scintigraphy.
Fields of Study & Subjects
Cardiac Imaging and Diagnostics
Cerebrovascular and Carotid Artery Diseases
Coronary Interventions and Diagnostics
Publication details
- Journal / source
- Circulation Reports
- Volume
- 8
- Issue
- 5
- Pages
- 857–859
- Publication date
- 13 February 2026
- Language
- EN