Outcomes of Liver Transplantation Without Alcohol Abstinence in Alcohol-Associated Hepatitis With Original MELD Score ≥30

Annals of Transplantation 2026 Open access

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Authors: Hao‐Chien Hung, TL Wu, Yin Hwa Lai, Jin‐Chiao Lee, Yu-Chao Wang, C F Cheng, Chen-Fang Lee, Ting-Jung Wu, Hong-Shiue Chou, Kun‐Ming Chan, Wei-Chen Lee
DOI: 10.12659/aot.951641
Cited by: 2

Abstract

BACKGROUND Achieving alcohol abstinence before standard liver transplantation (SLT) for alcohol-associated liver disease (ALD) is commonly accepted. However, the 3-month mortality rate for alcohol-associated hepatitis (AH) patients with extremely high Model for End-Stage Liver Disease (MELD) scores (≥30) exceeds 50%, suggesting insufficient time for these patients to achieve sobriety. Current data on outcomes for non-abstinent individuals in this high-risk group undergoing early liver transplantation (ELT) is limited. MATERIAL AND METHODS This single-center observational study (May 2002 to October 2023) involved 1410 liver transplantation (LT) patients. After excluding those with a MELD score

Fields of Study & Subjects

Alcohol Consumption and Health Effects Liver Disease Diagnosis and Treatment Liver Disease and Transplantation

Publication details

Journal / source
Annals of Transplantation
Publisher
International Scientific Information, Inc.
Volume
31
Pages
e951641–e951641
Publication date
26 January 2026
Language
EN