Analysis of risk factors and construction of nomogram model for enteral nutrition-related diarrhea in ICU patients

Objective: To analyze risk factors of enteral nutrition (EN) diarrhea in intensive care unit (ICU) patients and to construct nomogram model. Methodology: A retrospective analysis was conducted on 402 patients who received EN treatment in the ICU of Shanghai Blue Cross Brain Hospital from January 2022 to January 2025. They were divided into diarrhea group and non-diarrhea group based on the occurrence of EN diarrhea. We used univariate and multivariate logistic regression analysis to identify risk factors for EN diarrhea. Construct a nomogram model for the occurrence of EN diarrhea in ICU patients based on independent risk factors and conduct goodness of fit tests. Results: The incidence of EN diarrhea in ICU patients was 29.85% (120/402). Hypoproteinemia, abdominal surgery in the last five days, fasting time > 5 days, antibiotic use > 2 weeks, no gradual increase in EN preparations, oral potassium preparations, EN liquid infusion rate ≥ 100ml/h, albumin level ≥ 35g/L were identified as risk factors for EN diarrhea (p