Antioxidant properties of nano-formulated carotenoids and natural phenolic compounds against oxidative stress-induced health diseases

Radical oxygen species formed in human tissue cells via many endogenous and exogenous pathways cause extensive oxidative damage which has been linked to various human diseases. This investigation focused on the antioxidant potential of nano-carriers loaded with dietary natural antioxidants as phytotherapeutic agents. Main aim of this scientific review is to update the most recent advances in the application of nanoencapsulation to natural antioxidants against aging-related oxidative stress and associated pathological conditions. It provides an overview of recent in vitro and vivo trials on the potential of several nanoencapsulated antioxidant compounds (such as carotenoids, tocopherols, flavonoids and phenolic acids) to retard oxidative changes linked to carcinogenesis, cardiovascular and other serious health damages.