A Review of Candida auris

Background. Candida auris is an emerging, multidrug-resistant fungal pathogen ofsignificant public health concern. Noted for its environmental persistence and hightransmissibility, it poses a substantial threat in healthcare settings, particularly inintensive care units, driving the need for specific infection control protocols. Aim. The aim of this study was a comparative analysis of environmental disinfectionmethods used in the prevention and control of Candida auris in various countries andhealthcare facilities.Material and methods. This review analyzed literature from 2016-2025, sourcedfrom databases such as PubMed, alongside public health guidelines andepidemiological reports. A comparative analysis of the selected data wasconducted. Results. Disinfection strategies against C. auris primarily recommend chlorine- andhydrogen peroxide-based agents, with UV-C and vaporized hydrogen peroxide (VHP)noted as supplementary measures. A comparative analysis revealed significantinternational divergence, particularly regarding quaternary ammonium compounds(QACs), which are largely restricted except in specific contexts like India. Overallefficacy is highly variable and dependent on disinfectant selection, workflow, stafftraining, and the consistency of protocol implementation. Conclusions. Chlorine- and peroxide-based disinfectants are most effective against C.auris, while QACs are discouraged despite their localized use. To counter variabilityin international guidelines, a unified regulatory framework is recommended. Keyrecommendations include standardizing procedures, enhancing staff training, andmaintaining strict surveillance. Further research, including hospital case studies, isneeded due to insufficient current data.