Pre-clinical evidence-based insights into the therapeutic potential of Murraya koenigii (curry patta) with a focus on its future application as an anti-inflammatory drug

In recent years, there has been unprecedented growth in the use of plant-based herbal therapeutics for the management of various disease conditions. Murraya koenigii has a long history of use in India as a food enhancer and for its numerous therapeutic benefits. Various parts of the plant, including leaves, stems, and bark, are traditionally used to treat disorders such as dysentery, renal pain, gastrointestinal disturbances, and morning sickness. Leaf extracts of M. koenigii have been reported to possess cooling, anthelmintic, analgesic, antibacterial, anti-inflammatory, and antipruritic properties. In addition, the leaves are used in the management of leukoderma and as blood-purifying agents. Toasted leaves infused in water are traditionally used as a household remedy to control vomiting, while crushed leaves are applied topically to treat skin eruptions and soothe burns. The present review aims to provide an updated overview of the therapeutic potential of M. koenigii, with a particular emphasis on pre-clinical evidence supporting its anti-inflammatory activity.