The role of injectable regenerative treatments in the management of female pattern hair loss and their impact on patient-reported body image

Background: Female pattern hair loss (FPHL) is a common condition associated with signifi cant psychological distress, negatively impacting body image and quality of life. Injectable regenerative treatments, including platelet-rich plasma (PRP), polynucleotides (PN/PDRN), and exosome-based therapies, are increasingly used, though patient-reported outcomes remain underexplored. Aim: To review current evidence on injectable regenerative treatments for FPHL, focusing on their impact on body image and wellbeing. Methods: A structured narrative literature review was conducted using PubMed/MEDLINE, CINAHL, and Google Scholar. Studies involving women with FPHL receiving injectable treatments were included and synthesised narratively. Results: PRP shows consistent improvements in hair density and thickness with good safety. PN/PDRN and exosomes demonstrate emerging but limited evidence. Across all treatments, patient-reported outcomes are inconsistently assessed and rarely use validated measures. Conclusion: While injectable treatments show clinical promise, their impact on psychological wellbeing remains unclear. Further female-focused research incorporating validated patient-reported outcomes is needed to support holistic, evidence-based care.