Placental Digital Twin as a Communication Graph: Unifying Spatial Multi-omics, Placental Extracellular Vesicles, and Real-time Clinical Signals to Predict and Prevent Perinatal Complications -A Systematic Review and Translational Roadmap

Wiku Andonotopo; Muhammad Adrianes Bachnas; Julian Dewantiningrum; Mochammad Besari Adi Pramono; Wisnu Prabowo; Hariyasa Sanjaya; Ernawati Ernawati; Dudy Aldiansyah; Milan Stanojevic; Waskita Ekamaheswara Kasumba Andanaputra; Aloysius Suryawan; Ridwan Abdullah Putra

doi:10.13140/rg.2.2.32910.83523

Placental Digital Twin as a Communication Graph: Unifying Spatial Multi-omics, Placental Extracellular Vesicles, and Real-time Clinical Signals to Predict and Prevent Perinatal Complications -A Systematic Review and Translational Roadmap

2026 Open access

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Authors: Wiku Andonotopo, Muhammad Adrianes Bachnas, Julian Dewantiningrum, Mochammad Besari Adi Pramono, Wisnu Prabowo, Hariyasa Sanjaya, Ernawati Ernawati, Dudy Aldiansyah, Milan Stanojevic, Waskita Ekamaheswara Kasumba Andanaputra, Aloysius Suryawan, Ridwan Abdullah Putra

DOI: 10.13140/rg.2.2.32910.83523

Cited by: 0

Fields of Study & Subjects

Extracellular vesicles in disease Pregnancy and preeclampsia studies Single-cell and spatial transcriptomics

Publication details

Publication date: 1 January 2026