Value of histogram analysis of CT values in differential diagnosis of odontogenic keratocyst and ameloblastoma of the jaw

Objective To investigate the value of histogram analysis of CT values based on multislice CT (MSCT) in the differential diagnosis of odontogenic keratocyst (OKC) and ameloblastoma (AME) of the jaw. Methods A total of 32 patients with pathologically confirmed OKC and 59 patients with pathologically confirmed AME of the jaw were included in this study, and FireVoxel software was used for image processing and histogram analysis to obtain various histogram parameters, including the mean, standard deviation, variance, coefficient of variation, skewness, kurtosis, entropy, and percentiles (1st, 5th, 10th, 25th, 50th, 75th, 90th, 95th, and 99th) of CT values for lesions. The two-independent-samples t test or the Mann-Whitney U test was used for comparison of histogram parameters between OKC and AME of the jaw. A receiver operating characteristic (ROC) curve analysis was used to investigate the diagnostic efficacy of each parameter, and the area under the ROC curve (AUC) was also calculated. Results There were significant differences in the 5th and 10th percentiles of histogram parameters between OKC and AME of the jaw (Z=4.486, 2.058,P