Spatially selective fluorescent microscope based on electrically tunable liquid crystal lenses

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Authors: Maria Hovakimyan, Edward A. DeHoog, Simon Thibault, Tigran Galstian
Cited by: 0
References: 14

Abstract

The use of a large-aperture liquid crystal device in a fluorescent microscope is demonstrated to obtain a spatially selective excitation with an order of magnitude enhancement of the efficiency of the local fluorescence. Better than 1 µm lateral resolution of excitation is achieved by generating local electrically tunable lenses that can be moved to continuously scan the entire field of view. Changing their optical powers also allows for the continuous depth scanning of the excitation point. The proposed approach can be integrated into commercial microscopes as an "add-on" light source.

Fields of Study & Subjects

Advanced Optical Imaging Technologies Advanced Fluorescence Microscopy Techniques Liquid Crystal Research Advancements

Publication details

Journal / source
Applied Optics
Volume
65
Issue
6
Pages
1865–1865
Publication date
28 January 2026
Language
EN