Efficient algorithm for optimal wavelength selection in photoacoustic spectral unmixing

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Authors: Calvin Smith, Andrew Langley, Deeksha Sankepalle, Srivalleesha Mallidi, Brett E. Bouma, David Veysset
Cited by: 1
References: 29

Abstract

We present a method for numerically determining the optimal wavelengths to perform spectral unmixing in photoacoustic experiments. The proposed method employs a rugged-landscape-model-inspired stochastic hill-climbing approach that can reliably and efficiently converge to near-optimal wavelength selections. Compared to current methods, the algorithm consistently achieves superior spectral unmixing accuracy, as is demonstrated on synthetic and experimental data, while maintaining equivalent or faster run times, particularly in broad spectral ranges. The algorithm's adaptability with respect to computational efficiency makes it effective for both targeted offline wavelength optimization and opens up prospects for time-critical, real-time wavelength correction.

Fields of Study & Subjects

Thermography and Photoacoustic Techniques Photoacoustic and Ultrasonic Imaging Spectroscopy and Laser Applications

Publication details

Journal / source
Biomedical Optics Express
Publisher
Optica Publishing Group
Volume
17
Issue
5
Pages
2643–2643
Publication date
16 April 2026
Language
EN