Multimodal Optical Biosensing for Precision Medicine and Healthcare: Introduction to the feature issue

, is a curated selection of advances in optical biosensing technologies and their applications in healthcare and precision medicine. The demand for precise, real-time, non-invasive diagnostic and therapeutic tools has led to multimodal optical biosensing as the recent direction by merging complementary methodologies (e.g., optical biosensors, optical coherence tomography, optical biophysics and photobiology, optical diagnostics, microscopy, and terahertz spectroscopy and imaging). This feature issue contains a collection of articles that showcase advances in sensor design and validation, signal processing and imaging methodologies, as well as clinical translation. The contributions published showcase tremendous advances in the microscale and nanoscale development of biosensing platforms and are directed toward uses including disease diagnosis, monitoring, and therapeutic guidance via improved sensitivity, specificity, accuracy, robustness, reliability. This collection will provide an avenue for publishing new research, fostering interdisciplinary collaboration between technology and medicine development, and advancing the field of next-generation optical biosensors towards precision healthcare.