Aldosterone synthase inhibitors for hypertension: A breakthrough facing barriers to adoption

PLoS Medicine 2026 Open access

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Authors: Luke Joseph Laffin, Steven E. Nissen
DOI: 10.1371/journal.pmed.1004900
Cited by: 1
References: 11

Abstract

Despite many antihypertensive options, uncontrolled hypertension remains pervasive. Aldosterone synthase inhibitors show robust blood pressure reductions and have the potential to reshape hypertension treatment, though cost and access may impact broad adoption.

Fields of Study & Subjects

Hormonal Regulation and Hypertension Renin-Angiotensin System Studies Blood Pressure and Hypertension Studies

Publication details

Journal / source
PLoS Medicine
Publisher
Public Library of Science (PLoS)
Volume
23
Issue
2
Pages
e1004900–e1004900
Publication date
9 February 2026
Language
EN