Studies on prevalence of Hantavirus in small mammals in Southeast Asia: A systematic review and meta-analysis

PLoS neglected tropical diseases 2026 Open access

Read full text
Authors: Zixiao Guo, Hongxin Pan, Nini Wang, Yang Xiao, Qianwen Zhang, Changchun Ren, Puyu Liu, Qun Wu, Lijun Cai, Yu Cheng, Weixia Li, Dingwei Sun
DOI: 10.1371/journal.pntd.0014075
Cited by: 2
References: 40

Abstract

BACKGROUND: This study systematically analyzed the prevalence of Hantavirus (HVs) in small mammals across Southeast Asia to evaluate the risks of this zoonotic disease. METHODS: We searched the Web of Science, PubMed, Embase, Scopus, and Cochrane Library for studies published up to 6 February 2025, extracted data from 28 eligible studies. RESULTS: Meta-analysis revealed a pooled prevalence of HVs was 6.07% (986/11,806) in small mammals in Southeast Asia, with the highest prevalence in Indonesia (17.49%) and Singapore (10.53%). The prevalence was higher in samples detected by Enzyme-Linked Immunosorbent Assay (10.68%) and in rodents (8.07%). CONCLUSIONS: The results of our study highlight the urgency of strengthening surveillance in trade networks with Southeast Asia, particularly in high-risk areas such as Indonesia and Singapore, to mitigate the threat of imported zoonotic diseases.

Fields of Study & Subjects

Viral Infections and Vectors Vector-Borne Animal Diseases Vector-borne infectious diseases

Publication details

Journal / source
PLoS neglected tropical diseases
Publisher
Public Library of Science (PLoS)
Volume
20
Issue
3
Pages
e0014075–e0014075
Publication date
12 March 2026
Language
EN