Reframing Autism: A Theoretical Synthesis on Androgen-Mediated Cognitive Phenotypes and the Adaptive Feedback Model of Repetitive Behaviours

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Authors: Michele Di Salvo
Cited by: 0

Abstract

This article presents a comprehensive theoretical synthesis that critically examines and reframes two distinct facets of autism spectrum condition (ASC). First, it deconstructs the broad "extreme male brain" theory linking fetal testosterone to autistic traits, arguing against its reductive determinism. It proposes a more nuanced and constrained model wherein androgen-driven neural development may predispose a subset of individuals towards a specific cognitive phenotype characterized by systemizing strengths and savant abilities in STEM (Science, Technology, Engineering, and Mathematics) fields. Second, it advances a novel ethological framework, translating Konrad Lorenz's principles of learning and feedback to reinterpret restricted and repetitive behaviours (RRBs) not as pathological stereotypes but as purposeful, self-regulatory actions maintained by an internal positive feedback loop. The overarching argument champions a person-centric science of autism that integrates neurobiological insights with a functional, phenomenological understanding of behaviour, emphasizing profound individual heterogeneity and the critical need for hypotheses that respect this diversity. This work establishes a structured theoretical foundation for future empirical research into cognitive subtypes and the homeostatic functions of RRBs.

Fields of Study & Subjects

Autism Spectrum Disorder Research Genetics and Neurodevelopmental Disorders Sexual Differentiation and Disorders

Publication details

Journal / source
Revista de Discapacidad Clínica y Neurociencias
Volume
13
Issue
1
Pages
65–73
Publication date
13 January 2026
Language
ES