Previous Abdominal Surgery Is Not Associated With Adverse Pregnancy, Delivery, or Neonatal Outcomes in Women With Crohn's Disease: Results From the Pregnancy in Inflammatory Bowel Disease and Neonatal Outcomes Study

The American Journal of Gastroenterology 2026

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Authors: Erica Zurbuch, Uma Mahadevan, Samir M Shah, Xian Zhang, Ryan A. McConnell, Millie D. Long
DOI: 10.14309/ajg.0000000000003947
Cited by: 0
References: 10

Abstract

INTRODUCTION: Crohn's disease (CD)-related surgery may affect pregnancy outcomes. METHODS: We used the prospective Pregnancy in Inflammatory Bowel Disease and Neonatal Outcomes (PIANO) cohort to investigate pregnancy outcomes among women with CD by previous surgery by bivariate and multivariate analyses. RESULTS: Among 1,046 women with CD, 409 (39%) had previous surgery. Those with previous surgery had increased disease activity ( P < 0.001). On multivariate analysis, only disease activity (OR 1.14, 95% CI 1.06-1.22) and ileal disease (OR 2.19, 95% CI 1.26-3.83) were associated with preterm birth; not previous surgery. DISCUSSION: Previous surgery was not associated with adverse pregnancy or neonatal outcomes in CD.

Fields of Study & Subjects

Pregnancy and Medication Impact Inflammatory Bowel Disease Cardiovascular Issues in Pregnancy

Publication details

Journal / source
The American Journal of Gastroenterology
Volume
121
Issue
7
Pages
1772–1776
Publication date
11 February 2026
Language
EN