Intestinal Ultrasound to Assess Disease Activity After Induction With Upadacitinib in Acute Severe Ulcerative Colitis

ACG Case Reports Journal 2026 Open access

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Authors: Elena G. Gibson, Lindsey Shipley, Jordan D. Perchik, Kirk B. Russ, Mohamed Saleh Ismail
DOI: 10.14309/crj.0000000000001945
Cited by: 0
References: 5

Abstract

Intestinal ultrasound is a noninvasive, cost-effective tool to assess disease activity in ulcerative colitis (UC). Although upadacitinib, a selective Janus kinase 1 inhibitor, has demonstrated efficacy for induction therapy in patients with moderately to severely active UC, data in acute severe UC remain limited. We report on the use of intestinal ultrasound to assess treatment response after induction with upadacitinib in 3 patients hospitalized with acute severe UC.

Fields of Study & Subjects

Inflammatory Bowel Disease Microscopic Colitis Clostridium difficile and Clostridium perfringens research

Publication details

Journal / source
ACG Case Reports Journal
Volume
13
Issue
1
Pages
e01945–e01945
Publication date
1 January 2026
Language
EN