Doxycycline-Induced Gastrointestinal Injury for Potential Lyme Disease Exposure

ACG Case Reports Journal 2026 Open access

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Authors: Sapana R. Gupta, Ryan Liu, Lindsey Channen, Syed F Quadri, Amanda Pressman
DOI: 10.14309/crj.0000000000001946
Cited by: 1
References: 9

Abstract

Doxycycline is an antibiotic frequently used to treat tick-borne diseases. It is known to cause esophageal injury, although gastric injury is less often described. Few cases have been reported of gastrointestinal bleeding secondary to biopsy-proven doxycycline use. In the setting of widespread doxycycline use, it is important to recognize this drug-specific pattern of injury to guide appropriate patient management. This case demonstrates doxycycline-induced gastrointestinal injury and highlights characteristic histological findings.

Fields of Study & Subjects

Potassium and Related Disorders Poisoning and overdose treatments Pneumocystis jirovecii pneumonia detection and treatment

Publication details

Journal / source
ACG Case Reports Journal
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
13
Issue
1
Pages
e01946–e01946
Publication date
1 January 2026
Language
EN