Pioneering Endoscopic Submucosal Dissection in the West: Technique Introduction With a Comprehensive Case Report on the First Application for Oropharyngeal Squamous Cell Carcinoma

ACG Case Reports Journal 2026 Open access

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Authors: Ken Namikawa, Einar Stefan Bjornsson, Helgi Kristinn Sigmundsson, Geir Tryggvason, Sigfús Þór Nikulásson, Jon Gunnlaugur Jonasson, Magnús Konráðsson
DOI: 10.14309/crj.0000000000001956
Cited by: 0
References: 12

Abstract

Endoscopic submucosal dissection (ESD) for pharyngeal squamous cell carcinoma (SCC) has predominantly been performed in Asia but interest in this procedure is growing in the West. This report details the first known Western application of ESD for oropharyngeal SCC. A Caucasian female with superficial oropharyngeal SCC detected during endoscopic surveillance post-ESD for esophageal SCC underwent successful en-bloc resection without complications. Pathology confirmed SCC in situ with tumor-free margins. This case underscores the importance of mindset to include the pharynx in upper gastrointestinal endoscopy during surveillance within the gastroenterologist's domain and the potential for broader application of ESD in the West.

Fields of Study & Subjects

Head and Neck Cancer Studies Esophageal Cancer Research and Treatment Gastric Cancer Management and Outcomes

Publication details

Journal / source
ACG Case Reports Journal
Volume
13
Issue
1
Pages
e01956–e01956
Publication date
1 January 2026
Language
EN