Suspected Pyridostigmine-Related Hepatotoxicity
Abstract
Drug-induced liver injury describes the result of toxicity to the liver from offending drugs and/or their metabolites. Most cases are acute and resolve quickly after the medication is discontinued. It is a diagnosis of exclusion after ruling out other causes of liver injury, such as infectious and autoimmune etiologies. When drug-induced liver injury is suspected, the culprit can be determined by establishing a temporal relationship between drug exposure and the development of signs and symptoms of liver injury. In this case presentation, we discuss a patient who developed liver injury from pyridostigmine in the management of acute colonic pseudo-obstruction (Ogilvie syndrome).
Fields of Study & Subjects
Drug-Induced Hepatotoxicity and Protection
Poisoning and overdose treatments
Pharmacology and Obesity Treatment
Publication details
- Journal / source
- ACG Case Reports Journal
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Volume
- 13
- Issue
- 1
- Pages
- e01969–e01969
- Publication date
- 1 January 2026
- Language
- EN