Metastatic Malignant Melanoma Mimicking Pancreatic Adenocarcinoma
Abstract
Malignant melanoma is an aggressive cutaneous malignancy with a high propensity for lymphatic and distant metastasis. While it commonly spreads to lymph nodes, lungs, brain, liver, and the gastrointestinal tract, pancreatic involvement is generally rare, occurring in less than 1% of cases. We report a case of metastatic melanoma initially misdiagnosed as pancreatic adenocarcinoma. This case underscores the importance of maintaining a broad differential, obtaining tissue diagnosis, and using immunohistochemistry to avoid diagnostic anchoring and ensure accurate identification of metastatic melanoma.
Fields of Study & Subjects
Cutaneous Melanoma Detection and Management
Melanoma and MAPK Pathways
Brain Metastases and Treatment
Publication details
- Journal / source
- ACG Case Reports Journal
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Volume
- 13
- Issue
- 5
- Pages
- e02119–e02119
- Publication date
- 1 May 2026
- Language
- EN