Switching patients from cinacalcet to etelcalcetide: evaluation of predictors of efficacy in a retrospective cohort study
Abstract
BACKGROUND: The prevalence of SHPT depends on control strategy and target level of PTH. There is insufficient data for a justified choice of goals and strategy for the SHPT correction. AIM: A retrospective, multicenter, cohort study was conducted to assess the ethelcalcetide efficacy after six months in real world practice. The study sought to identify whether MBD-CKD characteristics are predictive of achieving the goals. MATERIALS AND METHODS: A study included 302 patients in 20 dialysis units in St. Petersburg. The primary endpoint was the proportion of patients who reached the target of PTH (300-599 pg/ml). The secondary endpoint was an absolute and relative decrease in PTH. The results were compared in subgroups with PTH (1000 pg/ml: 79% vs. 36%, p
Fields of Study & Subjects
Parathyroid Disorders and Treatments
Thyroid and Parathyroid Surgery
Dialysis and Renal Disease Management
Publication details
- Journal / source
- Problems of Endocrinology
- Publisher
- Endocrinology Research Centre
- Volume
- 71
- Issue
- 6
- Pages
- 4–14
- Publication date
- 18 January 2026
- Language
- RU