Real-World Evaluation of Dual-Axis Barbed PDO Knotless Sutures in Elective Soft Tissue Closure: A Multicenter Observational Study

Background: The knotless barbed sutures are designed to overcome the problems of ‎traditional knotted sutures through their ability to prevent knot slippage and maintain uniform ‎tension. The absorbable polydioxanone knotless suture PINION™ PDO with dual-axis barbs ‎provides both secure and efficient wound closure.‎ Aim: The study design aims to assess the clinical performance and safety aspects ‎of PINION™ PDO sutures during soft tissue approximation ‎ Methodology: The retrospective, multicenter observational research included 114 patients ‎who maintained complete follow-up data throughout 12 months. The study documented ‎demographic details along with wound characteristics, suture usage, closure time, and ‎complications at three different time points: discharge, 2 months, and 12 months.‎ Results: Most procedures were elective (91.23%), primarily involving the abdominal and ‎groin regions. The average time required for wound closure was 7.77 ± 2.13 minutes. ‎The postoperative complications remained low throughout the study period, with 8.77% at ‎discharge, 1.75% at 2 months, and no complications at 12 months. Surgical site infections, ‎together with serious adverse events, did not occur throughout the study.‎ Conclusion: The results showed that PINION™ PDO knotless sutures provided high safety ‎levels, easy handling, and efficient procedural performance. The study findings demonstrate ‎that this material may function as a suitable replacement for traditional sutures in ‎typical surgical procedures‎.