Effectiveness of 0.25% vs 0.375% Ropivacaine for Incisional Infiltration in Cesarean Delivery with Spinal Anesthesia

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Authors: Ahmad Habibi Siregar, Tasrif Hamdi, Rommy Fransiscus Nadeak, Arlinda Sari Wahyuni
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Abstract

Background: Postoperative discomfort subsequent to a caesarean delivery significantly influences the recuperation process and necessitates efficacious therapeutic intervention. Ropivacaine is a local anesthetic used to manage this pain, but there is limited comparison between its 0.25% and 0.375% concentrations.Objective: To evaluate the comparative efficacy of varying dosages of ropivacaine, specifically 0.25% and 0.375% concentrations, as local anesthetic infiltrates during the surgical procedure of Cesarean section incision.Methods: This randomized controlled trial (RCT) encompassed a cohort of 60 patients who underwent cesarean sections utilizing spinal anesthesia at Adam Malik Hospital, Medan, Haji Hospital Medan, Prof. Chairuddin P. Lubis USU Hospital Medan, and Putri Hijau Hospital Medan. The participants were stratified into three distinct groups: ropivacaine 0.25% (n=20), ropivacaine 0.375% (n=20), and a control group (n=20). Pain intensity was quantitatively assessed employing the numerical rating scale (NRS) at intervals of 2, 6, 12, and 24 hours postoperatively. Furthermore, the utilization of supplementary analgesics and the occurrence of adverse effects were meticulously documented. Statistical analysis of the data was conducted utilizing the Kruskal-Wallis test (p

Fields of Study & Subjects

Anesthesia and Pain Management Pain Management and Opioid Use Veterinary Pharmacology and Anesthesia

Publication details

Journal / source
JAI (Jurnal Anestesiologi Indonesia)
Volume
18
Issue
1
Pages
23–35
Publication date
26 January 2026
Language
EN