The Efficacy of High-Albumin Formula Supplementation (Albumed milk) on Serum Albumin Levels in Critically Ill Patients with Sepsis

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Authors: Wiwi Jaya, Arie Zainul Fatoni, Prataganta Iradat, Buyung Hartiyo Laksono
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Abstract

Background: Septic, an infection-induced condition, triggers an inflammatory response leading to life-threatening organ dysfunction and hypoalbuminemia. Albumed milk, containing extracts from egg whites and sprouts, has been considered a potential intervention to prevent hypoalbuminemia.Objective: This study aimed to evaluate the impact of albumed milk on elevating serum albumin levels in septic patients in the intensive care unit (ICU).Methods: An experimental study involved two groups totaling 40 patients. The control group received a standard ICU diet, while the treatment group received half of the regular ICU diet supplemented with 30 grams of albumed milk every 8 hours. Albumin levels were measured on days 0 and 3.Results: A significant reduction in average albumin levels occurred in the control group at 0.605 units (p-value = 0.006). Conversely, the treatment group showed a non-significant decrease, with an average reduction in albumin level of 0.03 units (p = 0.839).Conclusion: Albumed milk administration preserves albumin levels in septic patients compared to control patients without albumed, who show albumin level reduction. This highlights the potential utility of albumed milk as a supplementary measure in mitigating septic-related hypoalbuminemia.

Fields of Study & Subjects

Clinical Nutrition and Gastroenterology Sepsis Diagnosis and Treatment Hyperglycemia and glycemic control in critically ill and hospitalized patients

Publication details

Journal / source
JAI (Jurnal Anestesiologi Indonesia)
Volume
18
Issue
1
Pages
44–55
Publication date
3 February 2026
Language
EN