Patient adherence and outcomes under long-term oxygen therapy: A multicenter study

BACKGROUND AND AIM:Long-term oxygen therapy (LTOT) improves survival and outcomes in chronic respiratory failure.This multicenter study assesses the factors affecting adherence in patients undergoing long-term oxygen therapy and evaluates its impact on the frequency of hospital visits. METHODS:Clinical and demographic data of patients receiving LTOT who were admitted to the study centers between January 1 and June 30, 2024, were recorded.Patients who adhered to LTOT for ≥15 hours per day, including both daytime and nighttime use, were classified as fully adherent.Data from adherent patients were compared with those of non-adherent patients.Factors affecting LTOT adherence were determined using logistic regression analysis.RESULTS: Among the 374 patients who met the inclusion criteria, 40.6% were classified as adherent to LTOT.Emergency room visits (median: 3/year) and hospital admissions (median: 1/ year) were more frequent among LTOT-adherent patients over the past year.Regression analysis identified a body mass index (BMI)