Fate of Brain Metastasis With Cerebrospinal Fluid Space Invasion Based on MRI Findings: Clinical Features and Factors Affecting Progression to Overt Leptomeningeal Metastasis

Brain Tumor Research and Treatment 2026 Open access

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Authors: Yoontae Hong, Haechan Song, Ho‐Shin Gwak, Yun‐Sik Dho, Sang Hoon Shin, Heon Jong Yoo, Kyu-Chang Wang
DOI: 10.14791/btrt.2026.0001
Cited by: 1
References: 13

Abstract

Background Parenchymal brain metastasis (BM) and its extended growth into cerebrospinal fluid (CSF) pathways or surgical spillage could result in leptomeningeal metastasis (LM).We defined BM with epipial spread or dural attachment on MRI as BM with CSF space invasion (BM-CSFi), regardless of CSF cytology results, and evaluated its clinical course after BM resection. MethodsWe retrospectively reviewed 297 patients who underwent craniotomy for BM excluding patients followed for

Fields of Study & Subjects

Brain Metastases and Treatment Glioma Diagnosis and Treatment Meningioma and schwannoma management

Publication details

Journal / source
Brain Tumor Research and Treatment
Publisher
XMLink
Volume
14
Issue
1
Pages
35–35
Publication date
1 January 2026
Language
EN