Facile direct formation of CuO nanoparticles from a novel coordination polymer: characterization and biological evaluation

Abstract A cost-effective calcination method achieved a successful synthesis of Copper oxide (CuO) nanoparticles by combining polyvinyl alcohol (PVA) precursors with para aminobenzoic acid (P-ABA) derivatives. The PVA thermal decomposition served as the primary synthesis method for integrating P-ABA to produce CuO nanoparticles. A group of analytical techniques provided the tools for the characterization of these nanoparticles. X-ray diffraction (XRD) analysis showed that the resulting crystals belonged to the monoclinic crystal system with an average particle diameter reaching 28 nm. The prepared CuO nanoparticles underwent thermal investigation through thermogravimetric analysis (TG) and its corresponding differential thermogravimetric (DTG) measurement. The Coats-Redfern and Horowitz-Metzger methods helped determine the kinetic parameters as well as thermodynamic properties of Δ H *, Δ G *, and Δ S *. TEM alongside SEM studies provided observations of nanostructures while investigating structural and morphological characteristics. FTIR spectroscopy identified functional areas that proved the substance’s presence. The antibiological assessment of synthesized CuO nanoparticles tested their effectiveness against both Gram-positive and Gram-negative bacterial strains and antifungal pathogens. The results demonstrated significant antimicrobial efficacy, highlighting the potential applications of CuO nanoparticles in biomedical and pharmaceutical fields.