Síntesis de micropartículas de cobre y su acción antibacteriana en una fórmula cosmética

Nanomaterials and microstructured materials have demonstrated significant potential across various fields, particularly in biomedical applications aimed at controlling microorganisms that exhibit resistance to conventional antibiotics. The skin serves as the body’s primary protective barrier, maintaining the balance of the cutaneous microbiota; however, when this barrier is compromised, susceptibility to infections caused by opportunistic bacteria increases. In this context, effective alternatives to traditional antimicrobials are required.In this study, copper microparticles were synthesized via chemical reduction and their antibacterial activity was evaluated. Minimum inhibitory concentration (MIC) assays revealed inhibition of Staphylococcus aureus ATCC 6538 and Pseudomonas aeruginosa ATCC 9027, with antibacterial effects observed at the highest tested volume (2000 µL). The particles exhibited an average size of 492 nm and a zeta potential of –36.06 mV, indicating moderate colloidal stability and a low likelihood of permeating intact skin.These findings suggest that copper microparticles represent a viable alternative for incorporation into cosmetic formulations intended for skin cleansing or as a complementary approach in acne management, providing an effective antibacterial option without promoting microbial resistance.