GABA-ergic system in the experimental diabetes

The Ukrainian Biochemical Journal 2026 Open access

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Authors: Hovik Hayrapetyan, N. Kh. Khachatryan, R. R. Balagyozyan, Balagyozyan V. R., Mardanyan Ss, A Antonyan
DOI: 10.15407/ubj98.01.020
Cited by: 0

Abstract

γ-Aminobutyric acid (GABA) is a non-proteinogenic amino acid, neurotransmitter and concurrently trophic factor in the non-neuronal peripheral tissues. GABA is involved in the pathophysiology of endocrine disorders, in particular, diabetes mellitus (DM). This review summarizes the effects of GABA-ergic system components on the development of experimental diabetes induced in laboratory animals. The beneficial effect of GABA-associated amino acids mixtures in the DM treatment is discussed. Keywords: diabetes experimental models, ethanolamine-O-sulfate, GABA, GABA-ergic system, GABA-supporting complex

Fields of Study & Subjects

GABA and Rice Research Neuroscience and Neuropharmacology Research Aldose Reductase and Taurine

Publication details

Journal / source
The Ukrainian Biochemical Journal
Volume
98
Issue
1
Pages
20–29
Publication date
17 February 2026
Language
EN