Rare but Severe Lung Toxicity With Trimethoprim-Sulfamethoxazole

AAP Grand Rounds 2026

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DOI: 10.1542/gr.55-3-30
Cited by: 0

Abstract

Source: Ahmadi F, McArthur E, Garcia-Bournissen F, et al. Trimethoprim-sulfamethoxazole and acute respiratory failure in adolescents and young adults. 2025;8(11):e2545251; doi: 10.1001/jamanetworkopen.2025.45251.Investigators from ICES (Institute for Clinical Evaluative Sciences), Toronto, and Western University, London, Ontario, Canada, conducted a retrospective study to assess the association between trimethoprim-sulfamethoxazole (TMP-SMX) usage and acute respiratory failure in adolescents and young adults. For the study, they used administrative health databases to identify 2 cohorts of individuals 10 to

Fields of Study & Subjects

Pneumonia and Respiratory Infections Pharmacovigilance and Adverse Drug Reactions Drug-Induced Adverse Reactions

Publication details

Journal / source
AAP Grand Rounds
Volume
55
Issue
3
Pages
30–30
Publication date
1 March 2026
Language
EN