Towards in vivo MRI axon radius mapping: insights from MRI-scale histology and experimental validation
Abstract
Axons are micrometer-thin cables in the brain whose size is a potential biomarker for neurological disorders. While magnetic resonance imaging can, in theory, detect axon size, quantitative experimental proof has so far been lacking. We provide this proof via comparison with millions of axons from human brain microscopy and identify remaining challenges for clinical adoption.
Publication details
- Journal / source
- TUHH Open Research
- Publication date
- 1 January 2026
- Language
- EN